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No one yet knows the precise pharmacological mechanism by which semaglutide produces allodynia

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Semaglutide can decrease your appetite and make you feel like you dont need to eat as much

Patients should: tell their prescriber if they are planning a pregnancy use appropriate contraception where advised stop treatment and seek medical advice if pregnancy occurs discuss alternative treatment when semaglutide is being used for diabetes avoid using GLP-1 medicines during breastfeeding unless specifically advised by an appropriate clinician The MHRA advises that GLP-1 medicines should not be used during pregnancy, while trying to conceive or during breastfeeding because there is insufficient evidence to establish safety for the baby