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Furthermore, this review summarizes current research and pharmacological developments involving natural compounds, synthetic agents, and NAD + precursors as SIRT1 activators, assessing their feasibility in multi-target interventions and clinical applications

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Semaglutide, the active compound in medications like Ozempic and Wegovy, has helped millions of patients achieve meaningful weight losswith clinical trials showing average reductions of 1522% body weight over 68 weeks

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