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The liver fat (LF) reduction at 24 weeks was -42.9% (1 mg), -57.0% (4 mg), -81.4% (8 mg), -82.4% (12 mg) and +0.3% (placebo)[3]

Importantly, women exhibited a more pronounced reduction in AC and FMT, whereas men demonstrated significant decreases in overall BW and total FBM, as well as in regional fat, particularly in the arms

Understanding the specific dose you are using helps calibrate expectations for both benefits and side effects

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Most of these medications are administered via subcutaneous injection, with dosing frequencies ranging from twice daily to once weekly depending on the specific formulation

See our main article on where to get Retatrutide to learn more about other options.