Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets
Alhadeff, PhD, senior study author After reviewing this study, Shruti Pandiri, MD, assistant professor of medicine in the Division of Endocrinology with the Center for Weight Loss & Metabolic Health at Hackensack University Medical Center in New Jersey, told MNT the findings of this study have the potential to lead to the development of GLP-1-based obesity drugs with improved tolerability
Decreased appetite and gastrointestinal disorders (most commonly nausea) were reported more frequently with liraglutide (Supplementary Table 3)
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While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say
Carnitine palmitoyltransferase II (CPT2) or carnitine deficiency should be considered in treatment refractory migraine