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doi: 10.1016/j.neurobiolaging.2015.05.022 416 ZhanX.StamovaB.JinL.-W.DeCarliC.PhinneyB.SharpF

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This systems-level knowledge has sparked increased interest in integrated therapy that combine microbiome manipulation with immune-targeted medicines to produce long-term disease improvement [184]

[15] [16] These aldehydes react with unmodified lysine residues, resulting in cross-linking collagen and elastin, which is essential for stabilization of collagen fibrils and for the integrity and elasticity of mature elastin

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