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3 Inflammatory cytokines have a principle role in the pathogenesis of OA

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Nature 597:533538 Korsten SGPJ, Peracic L, van Groeningen LMB, Diks MAP, Vromans H, Garssen J, Willemsen LEM (2022) Butyrate prevents induction of CXCL10 and non-canonical IRF9 expression by activated human intestinal epithelial cells via HDAC inhibition

With CJC-1295/Ipamorelin, the two-month mark is when cumulative GH optimization becomes most apparent

May support joint mobility, flexibility, and functional performance by improving softtissue quality and structural resilience over time

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