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The role of pharmacists in managing adverse events related to immune checkpoint inhibitor therapy

More serious potential adverse effects include pancreatitis, gallbladder disease (cholelithiasis, cholecystitis), acute kidney injury (especially with dehydration), and increased risk of hypoglycemia when used with insulin or sulfonylureas

doi: 10.1111/dom.14843, 53 GibbonsC.BlundellJ.Tetens HoffS.DahlK.BauerR.BaekdalT

In the future, the integration of metabolomic readouts, single-cell and spatial transcriptomic localization, and metabolic modeling analysis is expected to establish a research framework of metabolic stratification-target selection-efficacy prediction, thereby reducing the risk of failed extrapolation across different diseases or populations (138)

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Here, we investigated how T cells respond and adapt to subphysiological temperatures