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When vitamin A deserves review Very restrictive or very low-fat diets Fat malabsorption or chronic diarrhea Pancreatic, biliary or inflammatory gastrointestinal disease Significant liver disease or impaired nutrient storage Poor night vision or other signs suggesting vitamin A deficiency Persistent low ceruloplasmin after protein and mineral factors are corrected Why high-dose vitamin A is not automatic Preformed vitamin A is stored in the liver

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After 64 weeks, participants taking oral semaglutide 25 mg achieved an average weight loss of 16.6% with full treatment adherence, compared to 2.7% with placebo

Thus, these trials are not thoroughly discussed in this review