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Clinicians should apply clinical judgement to select an individualised approach and may choose between: A one-to-two-week washout before semaglutide initiation, which is preferred for patients with significant side effects

Bacterial community mapping of the mouse gastrointestinal tract

Combination therapy: an upcoming paradigm to improve kidney and cardiovascular outcomes in chronic kidney disease

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Clinical trial data suggests retatrutide produces greater weight loss than tirzepatide (24-29% vs 20-22%), but with higher rates of side effects

People who have had bariatric surgery Previous bariatric surgery, particularly gastric bypass, permanently alters the digestive anatomy in ways that reduce B12 absorption