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Table 1 illustrates that the most significant obstacles to progress across these systems have not been a lack of physiological relevance, but unresolved pharmacologic, technological, or conceptual challenges

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Currer J, Harrison DE

The treatment also promotes collagen production, which helps reduce wrinkles, fine lines, and sagging skin, making it a popular choice among those seeking anti-aging benefits in Kesnand , Shirur , Shikrapur , and Sanaswadi

Second, comprehensive comorbidity indices (such as the Charlson comorbidity index), as well as structured data on smoking and alcohol consumption, were not systematically documented in the retrospective records and therefore could not be incorporated into the analysis