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Dose NAD+ precursors in the morning alongside 5-Amino-1MQ to align with circadian synthesis peaks

By repairing gut mucosa, dampening systemic cytokine release, and modulating immune pathways, they help stabilize the gutbrain axisa key regulator of nocturnal comfort and sleep continuity

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Extended Data Figure 8 Structures of class B GPCR ligands bound to NTDs

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