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age = 58 13.3 years, BMI = 25.8 2.5 kg/m 2 )

As well as indirect effects on several energy-metabolizing regions (Roh & Choi 2023)

Huang et al., 2020

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Part of the antioxidant capacity of serum is due to the presence of GSH and the reduced capacity could be associated with a general reduction in GSH due to its conjugation with NAPQI

These studies lay a foundation for developing dual IGF-IR/InsR inhibitors such as BMS-754807 and linsitinib (OSI-906)