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Intratumoral Distribution of Lactate and the Monocarboxylate Transporters 1 and 4 in Human Glioblastoma Multiforme and Their Relationships to Tumor Progression-Associated Markers

When GLP-1 binds to these receptors, it can shift macrophages from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, inhibit the production of pro-inflammatory cytokines like TNF-, IL-1, and IL-6, increase anti-inflammatory adiponectin, and inhibit NF-B, a key regulator of pro-inflammatory gene expression

In terms of lipid profile, the LC group had markedly higher levels of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A1 (Apo-A1) than those receiving the placebo

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