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it is foundational
[DOI] [PMC free article] [PubMed] [Google Scholar] 139.Moons R., Konijnenberg A., Mensch C., Van Elzen R., Johannessen C., Maudsley S., Lambeir A.M., Sobott F
Faster return to running through effective treatment carries significant practical value for serious runners
Initially identified as a growth factor that stimulates the differentiation of bone marrow progenitor cells into granulocytes and macrophages, GM-CSF also activates various signaling pathways, including JAK/STAT, MAPK, and PI3K, through JAK2 activation, thereby influencing immune functions (6265)
Supplementation with 500-1,000 mcg daily or regular monitoring of serum B12 levels is advisable for at-risk individuals