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Circulation 1999;100:11341146

The drug's primary actions on GLP-1 receptors do not appear to involve effects on the gastrointestinal mucosa that would predispose to bleeding

GHK-Cu is a naturally occurring tripeptide composed of three amino acids: Glycine Histidine Lysine When bound with copper ions, it forms the biologically active compound GHK-Cu

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Additionally, in SLE patients T cells, SIRT2 promotes Th17 cell differentiation and inhibits CD4 + T cell production of IL-2, correcting abnormal expression of IL-17A and IL-2, and benefiting CD4 + T cells in lupus prone mice and SLE patients (101)