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In cell cultures, homocysteine induces programmed cell death in human vascular endothelial cells by interfering in protein syntheses.5 Because of its similarity to methionine, homocysteine can enter the protein biosynthetic apparatus

J Neurochem 1994;62:1530-1538 57 -Arduini A ea

This structural modification also reduces its binding affinity to IGF binding proteins, allowing it to remain bioactive in circulation significantly longer than endogenous IGF-1

Rudman D, Feller AG, Cohn L, Shetty KR, Rudman IW, Draper MW

That means compounding pharmacies under 503A cant legally compound it for now

SPCD is inherited in an autosomal recessive manner, with mutated alleles coming from both parents