In a chinchilla model of acute acoustic trauma, HPN-07 itself enhanced auditory/cochlear functional recovery, and reduced loss of cochlear HCs, afferent nerve fibers in the spiral lamina and fibrocytes within the spiral ligament 33
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Irritant treatments including injections such as prolotherapy, PRP (Platelet Rich Plasma) and ABI (Autologous Blood Injections) and minimally invasive surgeries such as percutaneous tenotomy are increasingly popular
For endometriosis, most of the pipeline consists of repurposed medicines and devices providing pain management and halting or slowing the progression of the disease (hormonal medicines), with a limited number developed to address the underlying pathology (i.e