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Elevated homocysteine can damage the delicate lining of your blood vessels, causing inflammation and making them less flexible

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Mallone, R

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As a result, this leads to diminished production of NO, prostaglandin E2 (PGE2), and ROS, along with decreased levels of inducible iNOS, cyclooxygenase-2 (COX-2), and cytokines (Min-Ji et al., 2013)

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In addition, lower levels of folate in the brain are associated with higher blocking FRAA titers

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