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They not only synthesize different components of dermal matrix, but also produce a number of growth factors that are involved in a multitude of cellular pathways regulating cell migration and proliferation, angiogenesis, epithelialization, and so forth

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Since GST is a dimer, this antibody cross-linking of GST can cause formation of the multimeric GST-fusion/ligand complex

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This is particularly crucial given its potential impact on various cellular signaling pathways, which could pose serious risks