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FIGURE 4 3.5 FOXO4-DRI inhibits FOXO4-P53 binding and promotes P53 phosphorylation To further elucidate the specific mechanism of FOXO4-DRI in anti-aging, we induced senescence in endothelial cells under OGD conditions and treated these cells either PBS or FOXO4-DRI

After reconstitution with 1 to 2 mL of bacteriostatic water, the solution is stable for 4 weeks at +4C

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Gawryluk et al., 2011)

The gene encoding the IGF-1 receptor maps to human chromosome 15q25-q26 in the vicinity of the fes oncogene