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To assess oxidative stress levels, hippocampal tissue samples were also collected

Increased body weight and fat mass after subchronic GIP receptor antagonist, but not GLP-2 receptor antagonist, administration in rats

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Our findings, which utilize a novel CSMN reporter line with TDP-43 pathology, not only reveal the presence of metabolomic defects at an early stage of the disease, but also suggest that proper modulation of metabolomic imbalance could offer therapeutic strategies to improve the integrity of mitochondria, and thus the health of diseased UMNs

Rybelsus (Oral Tablet): Rybelsus, approved in 2019, represents a significant technological achievement as the first and only oral GLP-1 receptor agonist