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In T2D patients (n = 25, age 2565), consumption of 1 g L-citrulline twice a day for 4 weeks reduces the T2D-induced increase in arginase activity and increases plasma nitrites, effects corroborated by improvement of ACh-induced relaxation in ex vivo mouse aortic rings incubated (24-h) in low or high glucose-containing media and increases in NO production in ECs treated with high glucose (Shatanawi et al., 2020)
The injections are believed to enhance energy levels, boost metabolism, and potentially aid in weight loss indirectly by supporting an active lifestyle
6.2 Neural damage mechanisms The molecular disruptions outlined above initiate a series of cascading effects, leading to neural damage through oxidative stress, excitotoxicity, and demyelination
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