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As mitochondrial membranes are impermeable to coenzyme A (CoA) esters and long-chain fatty acids, binding of l-carnitine to acetyl groups via carnitine acyltransferase is essential for the shuttle of the acetylated fatty acids into the mitochondria and for their subsequent -oxidation in the matrix (Figure 1) [4]

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Technical References and Further Reading By contrast, Briere DA, et al

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