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Data Collection and Charting Study Selection To identify the studies to be included, two authors (CEBM and AFSR) independently scanned the title and abstract of every record retrieved in the search

This can all lead to dehydration

Torre and Dierssen [75] warned that many clinical trials in DS patients have limitations, such as poor design, a reduced number of participants, a lack of methods for the neuropsychological evaluation of patients, and the dependence on the IQ of individuals

Some researchers notice nothing significant initially

Reason: Improved clarity, vocabulary, and technical accuracy while maintaining the original meaning