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Additional information Competing interests The authors declare that they have no competing interests Authors' contributions NSG wrote the manuscript and performed the experiments and analyzed the samples

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Recently, Costantini et al

So many of my clients struggle not just with blood sugar instability, but with disrupted interoceptionblunted hunger/satiety cues, emotional eating, and poor nutrient sensing after years of stress, alcohol use, or ultra-processed food

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And participants taking the semaglutide lost about 14% of their body weight, and they had significantly greater reductions in knee pain and improvements in physical function compared with the placebo group