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First characterized in 1977 from rabbit brain tissue extracts

PubMed Wadden, T.A., Chao, A.M., Machineni, S., Kushner, R.F., Ard, J., Srivastava, G., et al

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In line with evidence accrued in patients with T2D, incretin-based therapies produced a favorable effect on traditional cardiovascular risk factors, such as lipids and blood pressure, and even reduced the risk of major cardiovascular events and heart failure-related events in individuals with obesity, as recently demonstrated for the first time in the SELECT trial with semaglutide 2.4 mg once-weekly