Other alternatives to Contrave or Wegovy include: Ozempic (semaglutide): once-weekly injection approved for people with type 2 diabetes, sometimes used off-label for weight loss Rybelsus (semaglutide): oral semaglutide tablet taken once daily Victoza ( liraglutide ): daily diabetes injection, available in a lower-cost generic version Metformin : generic diabetes medication that has shown modest amounts of weight loss in clinical studies , though it isnt approved for weight management
If you experience persistent or severe side effects, your prescriber may recommend slowing the dose escalation, dropping back to a lower dose temporarily, or trying a formulation with additives like glycine and B12 that can help reduce gastrointestinal symptoms
People at Risk of Vitamin B12 Deficiency Due to vitamin B12 requiring the protein "intrinsic factor" to be effectively used for the body, certain people are at higher risk of vitamin B12 deficiency than the general population
These brand-name medications all contain semaglutide, a glucagon-like peptide-1 (GLP-1) agonist
Shahid S, Khan A, Shahid W, Rehan M, Asif R, Nisar H, et al
Int J Mol Sci 20(23):5896 McGrath EP, Centonze FG, Chevet E, Avril T, Lafont E (2021) Death sentence: the tale of a fallen endoplasmic reticulum
