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Acknowledgements The authors would like to thank the faculty and administration of Jinnah Sindh Medical University and Kabul University of Medical Sciences for their academic and institutional support

Calcification causes blood vessels to harden and thicken, which means the heart has to work harder to pump blood around the body

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These drugs, such as Novo Nordisks Wegovy and Ozempic, have been proven to aid in weight loss and improve metabolic function

If someone loses weight and they experience disease remission, how long will this last

Track symptom scores, weekly skin photos, joint pain scale, bowel habits, and energy levels