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doi: 10.1016/j.tiv.2016.01.014 78 WangNZhouYFuCWangHHuangPWangBet al

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Uniquely, Lactobacillus relative abundance was dramatically higher in the 5A-1MQ-treated group switched from WD to LD compared to all other groups (Fig

Moreover, our study provides a mechanistic framework that could potentially explain other opioid-related side effects beyond constipation that may arise through modulation of central autonomic pathways (e.g., nausea, urinary retention, pruritus, and respiratory suppression) 41,42,43