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MiRNAs play important roles in basic cellular functions related to development, cellular differentiation, proliferation, apoptosis, cell-cycle control, metabolism and cancer (Iorio and Croce 2012)
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Although targeting glutamine metabolism is a promising strategy for cancer therapy, there are many hurdles to be overcome before we develop a clinically effective drug
The binding and structural studies of FOXO4-DRI with p53 which are reported in this manuscript are related to the patent
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