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doi: 10.1126/science.123.3191.309 189 HolmgrenABjrnstedtM

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However, all original studies included in this meta-analysis were approved by their respective institutional review boards and were conducted in accordance with the Declaration of Helsinki

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Motor performance as assessed by the MDS-UPDRS part 3 test battery in the off state (no l-DOPA given) did not change at all in the drug group after 12 months of treatment, while the control group deteriorated rapidly over time

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10.1016/0167-4889(86)90178-3 Biochim

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