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Subsequent work established that the peptide was naturally complexed with copper in plasma and that both the peptide and the copper were necessary for its biological effects

FDA approval came after a robust series of placebo-controlled trials with thousands of participants of varying ages

Antioxidants, such as vitamin C (Vit-C), vitamin E (Vit-E), glutathione, and N-acetylcysteine, represent a potential therapeutic strategy

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