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Both male and female mice treated with intranasal GHK-Cu had significantly lower concentrations of NFL-1 in the frontal cortex compared to intranasal saline treated cohorts (Figure 4C) indicating GHK-Cu was able to attenuate axonal damage associated with brain aging in C57BL/6 mice

Here we used Acetyl-l-carnitine and alpha lipoic acid (add link to product?) and phosphatidylcholine

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The Nrf2 protein then translocates into the cell nucleus, where it binds to the Antioxidant Response Element (ARE) on the DNA

10.1073/pnas.1403215111 Proc

Hence, they require gentle treatment