Patients should be advised to: Eat smaller, more frequent meals rather than large portions, which can overwhelm delayed gastric emptying Avoid high-fat, greasy, or spicy foods that are more difficult to digest and may exacerbate nausea Stay well-hydrated with small sips of water throughout the day, particularly important if vomiting occurs Eat slowly and chew thoroughly to facilitate digestion Avoid lying down immediately after eating
In clinical trials, 12%--18% of people taking Mounjaro and 25%--29% of people taking Zepbound reported nausea
Trial averages at the highest dose (12 mg) reached around 24% body weight loss at 48 weeks, and around 28% at 68 weeks in the obesity plus knee osteoarthritis trial
This eliminates delays between approval and medication delivery
Why it matters Semaglutide works best as part of a nutrient-dense, whole-food approach
How much weight can I lose on a GLP-1 medication