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99% of Pacific Islanders have sufficient enzyme, Cytochrome P450 2D6 (CYP2D6), to metabolize kava, while from 79% to 88% of Caucasian populations have sufficient enzyme However, a study of 31 people in Hawaii who were regular kava drinkers showed a significantly greater elevation of two liver enzymes compared with people who were not kava drinkers

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[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Stoll F., Kantowski T., Laaser J., Kloiber U., Plitzko G., Mann O., Aberle J., Lautenbach A

Common side effects include gastrointestinal symptoms like nausea, vomiting, diarrhea, and constipation, as well as hypoglycemia and injection site reactions

In order to keep the weight off, maintain and improve your health, you must eat better and proper portions as cited in an earlier blog, plus exercise

This is common and does not always mean the medication has stopped working