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The review confirmed that animal and human studies demonstrate adequate protein nutrition is crucial for maintenance of GSH homeostasis, and that enteral or parenteral cystine, methionine, N-acetyl-cysteine, and L-2-oxothiazolidine-4-carboxylate are effective cysteine precursors for tissue GSH synthesis

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Zvaczki Z, Szllsi J, Kiss SA, Koloszr S, Fejes I, Kovcs L, et al

Although active enzyme can be expressed in Escherichia coli, the delE155 enzyme appears to be unstable in vivo

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Neurological symptoms caused by long-term deficiency may take several weeks to months to fully improve