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Interestingly, these same GLP-1R agonists are also potential treatments for obesity due to the potent suppressive effects on food intake and body weight that have been reported in both humans and animal models (2, 25, 26, 36, 43)

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The baseline HbA1c level was 8.10%, and oral semaglutide was better at reducing HbA1c levels at 52 weeks (trial product estimands: 1.30%, s.e

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