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Real-time quantitative PCR was carried out on the CFX384 Touch Real-Time PCR Detection System (BIO-RAD)

Whilst not explored in detail in the latter project, we observed that the addition of a C-terminal acyl chain further influenced the ability of each ligand to recruit G proteins and -arrestins to the GLP-1R, highlighting this feature as a modifier of GLP-1R efficacy in its own right

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doi: 10.1056/NEJMoa2032183 [DOI] [PubMed] [Google Scholar] 3

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