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Patients with pre-existing gout, hyperuricaemia, or chronic kidney disease may benefit from serum urate monitoring during treatment

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These effects are typically mild to moderate and tend to improve as the body adjusts to the medication and the dose is gradually increased

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Despite promising preclinical data, clinical trials in humans are extremely limited, and the compound remains largely experimental, with ongoing research required to fully characterize pharmacokinetics, optimal dosing, long-term safety, and potential off-target effects