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Biochem Biophys Res Commun 482:980986 Shao S, Wang GL, Raymond C et al (2017) Activation of sonic hedgehog signal by purmorphamine, in a mouse model of Parkinsons disease, protects dopaminergic neurons and attenuates inflammatory response by mediating PI3K/AKt signaling pathway

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Psoriasis pathophysiology is characterized by abnormal keratinocyte proliferation and immune cell infiltration in the dermis and epidermis involving the innate and adaptive immune systems, with important roles for dendritic cells and T cells, among other cells