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In research it serves as substrate for sirtuins (SIRT1-7), PARP enzymes and CD38, key regulators of cellular aging, DNA repair and metabolism

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Suppressing localization of TDP43 in the mitochondria inhibited TDP43-mediated neurotoxicity (Wang et al., 2016)

Statistical analysis We applied the inverse variance-weighted (IVW) method with a multiplicative random model as the main statistical analysis and performed the following methodologies to test the core assumptions of MR (relevance, exchangeability, and exclusion restriction)

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1 for a summary of the major pathways of paracetamol metabolism) [22, 23]