Gradual dose increases or titration is used to reduce side effects and improve the tolerabily of the medication
MT-1 was first developed as a sunless tanning agent, as its ability to bind to melanocortin receptor 1 causes skin to produce more melanin, turning it darker
76 RCTs with 77 data sets were included in the meta-analysis
Materials and methods The proposal of this study was approved by the animal ethics committee of the Hamadan University of Medical Sciences (IR.UMSHA.REC.1400.631), and all methods were carried out in accordance with relevant guidelines and regulations
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Both the dosage and method of administration were determined based on earlier studies, with the application dose of BPC 157 set at 20 g/kg, as indicated in the References [22,32,33,38,45]