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[149] High costs of Ozempic prompted some insurance companies to investigate and refuse to cover individuals with what the companies considered was insufficient evidence to support a diabetes diagnosis, alleging off-label prescribing for weight loss

Retatrutides Phase 3 TRIUMPH-4 trial, published in December 2025, showed participants on the 12mg dose lost an average of 28.7% of their body weight over 68 weeks, with nearly 40% of participants losing 30% or more

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Strictly avoid margarine, vegetable shortening, and all products listing them as ingredients

However, if vomiting persists, reach out to your healthcare provider to prevent dehydration, and they may recommend IV fluids or other measures to avoid complications