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PYY promoted the repair of Satb2 KO colonic organoids after irradiation and mitigates DSS-induced colonic mucosal damage Molecular experiments confirmed that PYY can rescue the metabolic dysfunction caused by Satb2 deficiency in colonic epithelium, but its role in epithelial repair remains unclear

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No change in cytokine release (4 h after reactivation) was observed when the CD8 + T cells were incubated in 21% or 5% oxygen, but when reactivation was performed at 1% oxygen, levels akin to the tumor microenvironment or sites of infection, ML226-treated CD8 + T cells showed reduced secretion of interferon (IFNy), granzyme B and Fas ligand (FASL

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