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Clinical significance of lipid transport function of ABC transporters in the innate immune system

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494,495 Subsequent multi-center studies also demonstrated high rates of complete and durable response in advanced melanoma patients administrated with T-VEC, 496,497 even for the local lesions of patients who developed acquired resistance to immune checkpoint blockade

In patients with active RA, the addition of low-dose sirolimus (0.5 mg every other day for 24 weeks) to conventional immunosuppressive therapy effectively increased Treg cell frequencies, reduced Th17 cell populations, and improved clinical disease activity (Chictr.org.cn identifier: ChiCTR-IPR-17010307) (240)