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The decrease in systolic blood pressure is aseparate entity of GLp-1 effect unrelated to weight loss [1]

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It is a hormone that your small intestine produces and has several functions that contribute to weight loss

JAMA Cardiol 10(7):696707

It also remains unclear how weight loss observed in these randomized controlled trials will generalize to real-world populations, said Nick Stucky, MD, PhD, vice president of Truveta Research, practicing infectious diseases physician at Providence Portland Medical Center, and an author on the paper