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Most liver toxins, including alcohol, produce damage to cell membranes via free radical generation

[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Ginsberg Y., Khatib N., Weiner Z., Beloosesky R

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While roGFP2 WT was completely oxidized at even very low PfGrx C32S/C88S (SSG) concentrations, 1 M PfGrx C32S/C88S (SSG) glutathionylated approximately 50% of 1 M roGFP2 C151S (SH) suggesting that the redox couples roGFP2 C151S (SSG)/roGFP2 C151S (SH) and PfGrx C32S/C88S (SSG)/PfGrx C32S/C88S (SH) have very similar redox potentials

[PMID: 18990082 DOI: 10.1517/14728220802517901] [DOI] [PubMed] [Google Scholar] 58.Pierson DJ

And, in terms of nutrition, theres evidence that eating a high-fat, high-sugar diet can interfere with your cellular NAD levels and, in turn, mitochondrial function