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Tirzepatide, a dual agonist of GIP and GLP-1 receptors, was approved for T2DM in 2022 and obesity/overweight in 2023 [33]

Additionally, lymphocytes play a significant role in chronic inflammation by secreting cytokines and participating in antigen-specific immune responses, thereby aiding the host in managing persistent infections and tissue damage [99]

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When you combine GLP-1 receptor agonists with SGLT2 inhibitors in patients with diabetic kidney disease, you are stacking two complementary mechanisms

While compounded formulations are prepared in FDA-regulated pharmacies, the FDA does not verify their safety or effectiveness