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Description

The accumulation of PUFA-OOH disrupts membrane architecture, enhances permeability, and yields reactive aldehydes such as 4-hydroxynonenal (4-HNE) and 4-hydroxyhexenal (4-HHE), all of which intensify cellular injury

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It also plays an essential role in folate and related one-carbon metabolism, where FAD is required as a cofactor for methylenetetrahydrofolate reductase (MTHFR), a key folate-metabolizing enzyme

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As an alternative to vector-based heterologous expression, integration of biosynthetic genes into A

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IGF-1 has immediate effects, whereas HGH has a longer loading period

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