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animal studies 52 have shown that intracerebral CRF injection can induce delayed gastric emptying and gastrointestinal dysmotility, exacerbating GERD-related functional symptoms

Promising, but still unproven at the level of evidence you'd want before calling it a first-line treatment

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To view or add a comment, sign in Recent analysis indicates that individuals who discontinue GLP-1 receptor agonist weight-loss medications, such as those targeting the GLP-1R protein, typically regain 60% of lost weight within a year

Wang Z, Wang Z, Lu T, et al

Quinacrine intensity was measured at each time point within a 300-nm-radius circular mask centred at the manually selected pixel (see Fig